Cefmenoxime hydrochloride
CAS No. 75738-58-8
Cefmenoxime hydrochloride( SCE-1365 )
Catalog No. M15880 CAS No. 75738-58-8
Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
50MG | 52 | In Stock |
|
100MG | 71 | In Stock |
|
200MG | 113 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCefmenoxime hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
-
DescriptionCefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.(In Vitro):Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.(In Vivo):Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria.
-
In VitroCefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.
-
In VivoCefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria. Animal Model:Male Jcl:ICR mice Dosage:40 mg/kg Administration: Subcutaneous injection; daily, for 7 days Result:Inhibited mortality rate of animals was 60% at a dose of 40 mg/kg.
-
SynonymsSCE-1365
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorPBPs| Fts1
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number75738-58-8
-
Formula Weight1059.58
-
Molecular FormulaC32H35ClN18O10S6
-
Purity>98% (HPLC)
-
SolubilityDMSO: 8 mg/mL
-
SMILESCN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.Cl
-
Chemical Name7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Tsuchiya K, et al. Antimicrob Agents ChemOthers. 1981 Jan;19(1):56-65.
molnova catalog
related products
-
Resorcine
Resorcinol crystallizes from benzene as colorless needles that are readily soluble in water alcohol and ether but insoluble in chloroform and carbon disulfide.
-
Mecillinam
Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
-
Erythromycin
Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.