Cefmenoxime hydrochloride

CAS No. 75738-58-8

Cefmenoxime hydrochloride( SCE-1365 )

Catalog No. M15880 CAS No. 75738-58-8

Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 52 In Stock
100MG 71 In Stock
200MG 113 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cefmenoxime hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.
  • Description
    Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic.(In Vitro):Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.(In Vivo):Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria.
  • In Vitro
    Cefmenoxime (SCE-1365) hydrochloride inhibits at least 90% of strains tested (MIC90) ranged from 0.06 to 8 μg/mL for the Enterobacteriaceae.Cefmenoxime (SCE-1365) hydrochloride inhibits MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.Cefmenoxime (SCE-1365) hydrochloride against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values ranging from ≤0.008 to 0.25 μg/mL.
  • In Vivo
    Cefmenoxime (SCE-1365) hydrochloride (40 mg/kg; i.h.; daily, for 7 d; male Jcl:ICR mice) improves the survival rate of mice infected with lung bacteria. Animal Model:Male Jcl:ICR mice Dosage:40 mg/kg Administration: Subcutaneous injection; daily, for 7 days Result:Inhibited mortality rate of animals was 60% at a dose of 40 mg/kg.
  • Synonyms
    SCE-1365
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    PBPs| Fts1
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    75738-58-8
  • Formula Weight
    1059.58
  • Molecular Formula
    C32H35ClN18O10S6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 8 mg/mL
  • SMILES
    CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.CN1N=NN=C1SCC2=C(N3C(=O)C(C3SC2)NC(=O)/C(=N/OC)/C4=CSC(=N4)N)C(=O)O.Cl
  • Chemical Name
    7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tsuchiya K, et al. Antimicrob Agents ChemOthers. 1981 Jan;19(1):56-65.
molnova catalog
related products
  • Resorcine

    Resorcinol crystallizes from benzene as colorless needles that are readily soluble in water alcohol and ether but insoluble in chloroform and carbon disulfide.

  • Mecillinam

    Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).

  • Erythromycin

    Erythromycin, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.